Networking for Life Scientists

Bryan Downie's Page

Bryan Downie Male Goettingen, Germany: 1rnxsd4j96big; Share

Discussions (1)

Bryan Downie's Friends

View All

Bryan Downie's Groups

Max Planck Institute of Experimental Medicine (4 members)
Goettingen Researchers (2 members)

View All

Profile

Research Category: Basic

Biological Expertise: Biochemistry, Cell Biology, Physiology

Current Research: Eag1 is a voltage-dependent potassium ion channel, normally only expressing the CNS, that has been implicated in tumor formation. Our research suggests that Eag1 contributes to oncogenesis by interfering with the normal cellular oxygen homeostasis pathway that regulates angiogenesis and metabolism.

Research Keywords: Eag1, prolyl hydroxylase, VHL, HIF, hypoxia, ion channels, potassium, cancer, VEGF, angiogenesis, tumor

Laboratory Skills: Cell Culture, Cloning, Electrophysiology, Flow Cytometry, Immunoblotting, Immunostaining, Programming Languages, Radioactive Labelling

Career Stage: Doctoral Student

University: University of Washington, Seattle
University of Göttingen, Germany

Publications: Weber, C., Mello de Queiroz, F., Downie, B.R., Suckow, A., Stuhmer, W., and Pardo, L.A. (2006). “Silencing the activity and proliferative properties of the human EagI Potassium Channel by RNA Interference.” The Journal of biological chemistry 281, 13030-13037 PubMed

Languages Spoken (in order of fluency): English, German

Bryan Downie's Blog

Blog of the Week #1

Each week we'll feature an exciting blog that is discussing matters of interest to life scientists! This week is Science and Reason! Please submit your own blog suggestions at the BotW blog.

Posted on June 3rd, 2008 at 3:30pm — No Comments (Add)

Comment Wall (1 comment)

You need to be a member of Vectorial to add comments!

Join this network

At 9:38pm on June 23rd, 2008, Amit Agarwal said…: Hi Bryan, this group seems quite interesting....

Hello, you need to enable JavaScript to use this network.